Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31252999 | 0.77 | RORC (0.51) | RORCOPRL1TAAR1SIGMAR1 | |
| SCHEMBL31243799 | 0.76 | OPRL1 (0.50) | RORCOPRL1SIGMAR1 | |
| SCHEMBL31593978 | 0.75 | RORC (0.47) | RORCOPRL1TAAR1SIGMAR1 | |
| SCHEMBL1807425 | 0.70 | OPRL1 (0.47) | RORCOPRL1 | |
| SCHEMBL31387399 | 0.67 | OPRL1 (0.47) | RORCOPRL1TAAR1SIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL1808226 | 0.65 | OPRL1 (0.45) | RORCOPRL1TAAR1SIGMAR1 | |
| SCHEMBL18579655 | 0.65 | OPRL1 (0.45) | RORCOPRL1TAAR1SIGMAR1 | |
| SCHEMBL17037682 | 0.64 | OTUD7B (0.56) | SIGMAR1OTUD7B | |
| SCHEMBL31387359 | 0.63 | OPRL1 (0.41) | RORCOPRL1TAAR1 | |
| SCHEMBL31387408 | 0.61 | SIGMAR1 (0.39) | RORCSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119343353-A | 2-Methyl-4 ',5' -dihydrospiro [ piperidine-4, 7' -thieno [2,3-c ] pyran ] derivatives as APOL1 inhibitors and methods of use thereof | 弗特克斯药品有限公司 | 2025-01-21 | — | — | CN | disclosed |