Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3123586 | 0.84 | KDM4E (0.54) | KDM4ETPSAB1CA2MLYCDHDAC6 | |
| SCHEMBL3765452 | 0.83 | ACKR3 (0.60) | ALDH1A1LMNAKDM4EKMT2ATPSAB1 | |
| SCHEMBL13056746 | 0.83 | ACKR3 (0.60) | ALDH1A1LMNAKDM4EKMT2ATPSAB1 | |
| SCHEMBL24331631 | 0.81 | CA2 (0.67) | KDM4EKMT2AMEN1CA2MLYCD | |
| SCHEMBL13212977 | 0.80 | CA2 (0.69) | KDM4EKMT2AMEN1CA2MLYCD | |
| SCHEMBL14720130 | 0.80 | CHIT1 (0.52) | ALDH1A1LMNAKDM4EKMT2ATPSAB1 | |
| SCHEMBL4592027 | 0.80 | KMT2A (0.54) | ALDH1A1LMNAKDM4EKMT2ATPSAB1 | |
| SCHEMBL8716820 | 0.79 | TPSAB1 (0.65) | ALDH1A1LMNAKDM4EKMT2ATPSAB1 | |
| SCHEMBL8716814 | 0.79 | TPSAB1 (0.65) | ALDH1A1LMNAKDM4EKMT2ATPSAB1 | |
| SCHEMBL27380497 | 0.79 | TPSAB1 (0.65) | ALDH1A1LMNAKDM4EKMT2ATPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010055304-A2 | PHARMACEUTICAL COMPOUNDS | SAREUM LIMITED (GB) | 2010-05-20 | — | — | WO | disclosed |
| EP-2170849-A1 | OXAZOLE TYROSINE KINASE INHIBITORS | Sareum Limited (GB) | 2010-04-07 | — | — | EP | disclosed |
| WO-2008139161-A1 | OXAZOLE TYROSINE KINASE INHIBITORS | SAREUM LIMITED (GB) | 2008-11-20 | — | — | WO | disclosed |