Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28864576 | 0.97 | CES2 (0.33) | KDM4EALDH1A1GAACES2CES1 | |
| SCHEMBL11433359 | 0.83 | POLB (0.38) | KDM4EALDH1A1CES2CES1HSP90AA1 | |
| SCHEMBL31245687 | 0.78 | ATM (0.37) | KDM4EALDH1A1GAAMEN1TP53 | |
| SCHEMBL10878544 | 0.73 | TDP1 (0.31) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL1313656 | 0.73 | CYP1A2 (0.33) | KDM4EALDH1A1CES2CES1HSP90AA1 | |
| SCHEMBL25549138 | 0.73 | ALDH1A1 (0.33) | ALDH1A1CYP3A4HSD17B10SLC6A2SLC6A4 | |
| SCHEMBL10485205 | 0.70 | TSHR (0.33) | CES2CES1F2PRSS1 | |
| SCHEMBL5025415 | 0.69 | CYP2A6 (0.33) | HSP90AA1PAX8TDP1SLC6A2SLC6A4 | |
| SCHEMBL7753185 | 0.69 | CYP2D6 (0.30) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15859481 | 0.66 | CA1 (0.32) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219624-A | Dihydronaphthalene amide preparation method of class compound | 江苏吴中医药集团有限公司 | 2024-12-31 | — | — | CN | claimed |
| CN-119219624-A | Dihydronaphthalene amide preparation method of class compound | 江苏吴中医药集团有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-119219624-A | Dihydronaphthalene amide preparation method of class compound | 江苏吴中医药集团有限公司 | 2024-12-31 | — | — | CN | disclosed |