SCHEMBL31246036

SCHEMBL31246036

CC(C)(C)OC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)CCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 1/20 0.43
▸ TLR2 O60603 3/20 0.40
▸ ACE P12821 1/20 0.40
▸ KLK5 Q9Y337 1/20 0.39
▸ TDP1 Q9NUW8 2/20 0.38
▸ PAX8 Q06710 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ TLR1 Q15399 1/20 0.38
▸ MDM4 O15151 1/20 0.38
▸ TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30943695 0.93 KMT2A (0.41) KMT2ATLR2ACE
SCHEMBL31246035 0.90 KMT2A (0.47) KMT2ATLR2MDM4TP53
SCHEMBL17196273 0.89 KLK5 (0.46) KMT2AACEKLK5TDP1MAPT
SCHEMBL29539925 0.89 KLK5 (0.46) KMT2AACEKLK5TDP1MAPT
SCHEMBL20646383 0.89 KLK5 (0.46) KMT2AACEKLK5TDP1MAPT
SCHEMBL31478692 0.89 KLK5 (0.46) KMT2AACEKLK5TDP1MAPT
SCHEMBL30943632 0.87 KMT2A (0.46) KMT2ATLR2
SCHEMBL31309891 0.85 KLK5 (0.42) KMT2ATLR2KLK5TLR1
SCHEMBL31309835 0.84 KLK5 (0.43) KMT2ATLR2KLK5TLR1
SCHEMBL30874603 0.84 PAX8 (0.43) KMT2ATLR2TDP1PAX8TLR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4643877-A1 COMPOSITION OF CD40-BINDING MOLECULE AND PHARMACEUTICAL USE THEREOF Suzhou Suncadia Biopharmaceuticals Co., Ltd. (CN) 2025-11-05 — — EP disclosed
US-20250152722-A1 DRUG CONJUGATE OF GLUCOCORTICOID SHANGHAI SENHUI MEDICINE CO., LTD. (CN) 2025-05-15 — — US disclosed
EP-4470569-A1 DRUG CONJUGATE OF GLUCOCORTICOID Shanghai Shengdi Pharmaceutical Co., Ltd (CN) 2024-12-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250152722-A1 DRUG CONJUGATE OF GLUCOCORTICOID SHBG, CYP17A1, HSD17B7 KMT2A 2814/4885TLR2 3268/4885ACE 712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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