Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26969480 | 0.80 | L3MBTL1 (0.37) | HTR6L3MBTL1PTPN11MEN1KMT2A | |
| SCHEMBL29605374 | 0.80 | L3MBTL1 (0.37) | HTR6L3MBTL1PTPN11MEN1KMT2A | |
| SCHEMBL13834845 | 0.80 | BRD4 (0.45) | HTR6L3MBTL1PTPN11MEN1KMT2A | |
| SCHEMBL5074943 | 0.80 | CA1 (0.48) | HTR6L3MBTL1PTPN11CA2POLB | |
| SCHEMBL25422336 | 0.79 | HTR6 (0.61) | HTR6L3MBTL1MEN1KMT2ACA2 | |
| SCHEMBL30461646 | 0.79 | HTR6 (0.61) | HTR6L3MBTL1MEN1KMT2ACA2 | |
| SCHEMBL13835162 | 0.77 | HSD11B1 (0.41) | HTR6L3MBTL1PTPN11MEN1KMT2A | |
| SCHEMBL29387065 | 0.77 | PTPN11 (0.38) | L3MBTL1PTPN11MEN1KMT2ACA2 | |
| SCHEMBL8944259 | 0.76 | L3MBTL1 (0.67) | HTR6L3MBTL1PTPN11CA2CA9 | |
| SCHEMBL19320346 | 0.76 | PIM1 (0.40) | HTR6L3MBTL1PTPN11POLBALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4687883-A2 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | Caraway Therapeutics, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024211249-A2 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | CARAWAY THERAPEUTICS, INC. (US) | 2024-10-10 | — | — | WO | disclosed |