Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683087 | 0.82 | MAPT (0.55) | CYP3A4ALDH1A1TSHRTDP1MAPT | |
| SCHEMBL6864579 | 0.78 | TSHR (0.61) | CYP3A4ALDH1A1TSHRTDP1MAPT | |
| SCHEMBL17154337 | 0.78 | TSHR (0.61) | CYP3A4ALDH1A1TSHRTDP1MAPT | |
| SCHEMBL8094139 | 0.78 | CYP3A4 (1.00) | CYP3A4ALDH1A1TSHRTDP1MAPT | |
| SCHEMBL3482770 | 0.78 | CYP3A4 (1.00) | CYP3A4ALDH1A1TSHRTDP1MAPT | |
| 4,4'-Methylenedianiline SCHEMBL15105282 | 0.78 | CYP3A4 (1.00) | CYP3A4ALDH1A1TSHRTDP1MAPT | |
| SCHEMBL6362775 | 0.78 | CYP3A4 (1.00) | CYP3A4ALDH1A1TSHRTDP1MAPT | |
| 4,4'-Methylenedianiline SCHEMBL28001 | 0.78 | CYP3A4 (1.00) | CYP3A4ALDH1A1TSHRTDP1MAPT | |
| SCHEMBL1304762 | 0.78 | CYP3A4 (1.00) | CYP3A4ALDH1A1TSHRTDP1MAPT | |
| SCHEMBL9719313 | 0.76 | CYP3A4 (0.64) | CYP3A4ALDH1A1TSHRTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152826-B1 | CHEMICAL-MECHANICAL POLISHING COMPOSITION COMPRISING POROUS METAL-ORGANIC FRAMEWORK MATERIALS | BASF SE (DE) | 2013-07-17 | — | — | EP | disclosed |
| US-8372305-B2 | Chemical-mechanical polishing composition comprising metal-organic framework materials | BASF SE (DE) | 2013-02-12 | — | — | US | disclosed |
| US-20100178767-A1 | CHEMICAL-MECHANICAL POLISHING COMPOSITION COMPRISING METAL-ORGANIC FRAMEWORK MATERIALS | BASF SE (DE) | 2010-07-15 | — | — | US | disclosed |
| EP-2152826-A1 | CHEMICAL-MECHANICAL POLISHING COMPOSITION COMPRISING METAL-ORGANIC FRAMEWORK MATERIALS | Basf Se (DE) | 2010-02-17 | — | — | EP | disclosed |
| US-20090032023-A1 | CLOSED REVERSIBLE BREATHING APPARATUS HAVING A METAL ORGANIC FRAMEWORK | BASF SE (DE) | 2009-02-05 | — | — | US | disclosed |
| WO-2008142093-A1 | CHEMICAL-MECHANICAL POLISHING COMPOSITION COMPRISING METAL-ORGANIC FRAMEWORK MATERIALS | BASF SE (DE) | 2008-11-27 | — | — | WO | disclosed |