Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 3/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2762349 | 0.90 | POLB (0.62) | RAB9ATSHRALDH1A1POLBMEN1 | |
| SCHEMBL3038302 | 0.88 | MAPT (0.70) | MAPTRAB9ATDP1ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL23629626 | 0.86 | MAPT (0.67) | MAPTRAB9ATDP1ALDH1A1CYP3A4 | |
| SCHEMBL3773254 | 0.84 | SLC1A3 (0.58) | MAPTTSHRALDH1A1POLBMEN1 | |
| SCHEMBL4690088 | 0.84 | RAB9A (0.66) | MAPTRAB9ATSHRMEN1KMT2A | |
| SCHEMBL13343448 | 0.83 | TSHR (0.67) | MAPTRAB9ATDP1TSHRALDH1A1 | |
| SCHEMBL11415508 | 0.82 | MAPT (0.61) | MAPTRAB9ATDP1ALDH1A1CYP3A4 | |
| 4,4'-Methylenedianiline SCHEMBL3124731 | 0.82 | CYP3A4 (0.61) | MAPTRAB9ATDP1TSHRALDH1A1 | |
| SCHEMBL29135460 | 0.81 | PLA2G10 (0.65) | MAPTRAB9AALDH1A1POLBMEN1 | |
| SCHEMBL9319389 | 0.81 | POLB (0.79) | MAPTRAB9ATDP1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2825544-B1 | MODIFIED ISOCYANATE COMPOSITIONS AND METHODS OF PREPARING THE SAME | BASF SE (DE) | 2018-08-08 | — | — | EP | disclosed |
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |
| EP-0000815-B1 | PROCESS FOR PREPARING N-ARYL OR N-ARALKYL SUBSTITUTED URETHANES | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1982-01-27 | — | — | EP | disclosed |