Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.61 |
| ▸ | TYR | P14679 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.61 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.61 |
| ▸ | XDH | P47989 | 2/20 | 0.52 |
| ▸ | QPCT | Q16769 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | NEU2 | Q9Y3R4 | 1/20 | 0.50 |
| ▸ | GABRP | O00591 | 3/20 | 0.49 |
| ▸ | GABRD | O14764 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL313004 | 0.90 | ATM (0.52) | BACE1TYRPTPN1PTGS1PTPN12 | |
| SCHEMBL312050 | 0.88 | KDM4E (0.44) | BACE1TYRPTPN1PTGS1PTPN12 | |
| SCHEMBL312748 | 0.87 | TYR (0.44) | BACE1TYRPTPN1PTGS1PTPN12 | |
| SCHEMBL312223 | 0.86 | AKR1B1 (0.56) | XDHQPCTMEN1KMT2ATP53 | |
| SCHEMBL313540 | 0.84 | MAPT (0.41) | BACE1TYRPTPN1PTGS1PTPN12 | |
| SCHEMBL311784 | 0.84 | AKR1B1 (0.46) | MEN1KMT2ATP53CYP3A4MAPT | |
| SCHEMBL311791 | 0.84 | HPGD (0.51) | MEN1KMT2ATP53CYP3A4MAPT | |
| SCHEMBL326091 | 0.84 | ABL1 (0.42) | BACE1TYRPTPN1PTGS1PTPN12 | |
| SCHEMBL312609 | 0.83 | HPGD (0.42) | BACE1TYRPTPN1PTGS1PTPN12 | |
| SCHEMBL324201 | 0.82 | HPGD (0.61) | MEN1KMT2ATP53CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |