Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.34 |
| ▸ | HTR2B | P41595 | 6/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441084 | 0.86 | HDAC6 (0.38) | PPARGHTR2BSLC22A12RECQLLOXL2 | |
| SCHEMBL5031396 | 0.82 | CYP11B1 (0.38) | PPARGHTR2BSLC22A12RECQLLOXL2 | |
| SCHEMBL2783906 | 0.81 | HTR2B (0.44) | PPARGHTR2BHTR3A | |
| SCHEMBL31248498 | 0.79 | PPARG (0.35) | PPARGMTNR1AMTNR1BHTR2BSLC22A12 | |
| SCHEMBL19925815 | 0.72 | PPARG (0.69) | PPARGHTR2BHTR3ANPC1RAB9A | |
| SCHEMBL16632533 | 0.71 | MAOA (0.37) | LOXL2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5545134 | 0.71 | AGXT (0.34) | PPARGHTR2BSLC22A12LOXL2 | |
| SCHEMBL2249038 | 0.71 | LOXL2 (0.60) | HTR2BLOXL2MEN1KMT2ARAB9A | |
| SCHEMBL2786365 | 0.70 | TNKS (0.43) | HTR2B | |
| SCHEMBL1850465 | 0.70 | CYP11B1 (0.37) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024217519-A1 | PYRROLE SULFONYL DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 天地恒一制药股份有限公司 | 2024-10-24 | — | — | WO | disclosed |