SCHEMBL31248761

SCHEMBL31248761

CC(C)(C)OC(=O)NCc1ccc(-c2ccc(=O)[nH]c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.52
▸ HDAC1 Q13547 1/20 0.48
▸ SDCBP O00560 1/20 0.46
▸ SDC2 P34741 1/20 0.46
▸ NAMPT P43490 2/20 0.45
▸ MAPT P10636 3/20 0.44
▸ TDP1 Q9NUW8 2/20 0.44
▸ NPSR1 Q6W5P4 2/20 0.44
▸ RECQL P46063 1/20 0.44
▸ GAA P10253 1/20 0.44
▸ HPN P05981 1/20 0.44
▸ GPR119 Q8TDV5 1/20 0.43
▸ CA1 P00915 1/20 0.42
▸ CA2 P00918 1/20 0.42
▸ MEN1 O00255 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ XBP1 P17861 1/20 0.41
▸ GPR55 Q9Y2T6 1/20 0.41
▸ CYP17A1 P05093 1/20 0.41
▸ AKT1 P31749 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14353177 0.87 LMNA (0.49) L3MBTL1NAMPTMAPTTDP1GPR119
SCHEMBL29773322 0.87 BRD4 (0.52) L3MBTL1HDAC1MEN1KMT2AGRM2
SCHEMBL3180689 0.81 L3MBTL1 (0.61) L3MBTL1HDAC1SDCBPSDC2NAMPT
SCHEMBL2567630 0.80 HDAC1 (0.57) L3MBTL1HDAC1SDCBPSDC2NAMPT
SCHEMBL1691047 0.80 HDAC1 (0.67) L3MBTL1HDAC1SDCBPSDC2NAMPT
SCHEMBL19502096 0.80 CYP17A1 (0.53) NAMPTGPR119CA1CYP17A1
SCHEMBL18664387 0.79 HDAC1 (0.53) L3MBTL1HDAC1SDCBPSDC2NAMPT
SCHEMBL18664525 0.79 GRM2 (0.57) L3MBTL1HDAC1SDCBPSDC2NAMPT
SCHEMBL23959162 0.78 HDAC1 (0.61) L3MBTL1HDAC1SDCBPSDC2NAMPT
SCHEMBL506891 0.78 CYP17A1 (0.61) L3MBTL1HDAC1SDCBPSDC2NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720057-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) 2026-04-08 — — EP disclosed
WO-2024249888-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2024-12-05 — — WO disclosed
Send feedback