Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.55 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.55 |
| ▸ | NTSR2 | O95665 | 5/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 5/20 | 0.49 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.49 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.49 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.49 |
| ▸ | APLNR | P35414 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.48 |
| ▸ | REN | P00797 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29608298 | 0.91 | MAPK8 (0.52) | MAPK8MAPK9MAPK10NTSR2NTSR1 | |
| SCHEMBL30272472 | 0.89 | APLNR (0.57) | MAPK8MAPK9MAPK10NTSR2NTSR1 | |
| SCHEMBL30689267 | 0.87 | OPRK1 (0.59) | NMUR2NMUR1OPRK1OPRM1 | |
| SCHEMBL30285008 | 0.86 | MAPK8 (0.59) | MAPK8MAPK9MAPK10NTSR2NTSR1 | |
| SCHEMBL32679555 | 0.85 | MAPK8 (0.50) | MAPK8MAPK9MAPK10NTSR2NTSR1 | |
| SCHEMBL31384592 | 0.85 | NPY4R (0.60) | OPRK1OPRM1 | |
| SCHEMBL31384595 | 0.85 | NPY4R (0.60) | OPRK1OPRM1 | |
| SCHEMBL29607740 | 0.85 | MAPK8 (0.54) | MAPK8MAPK9MAPK10NTSR2NTSR1 | |
| SCHEMBL18176610 | 0.84 | OPRK1 (0.63) | NMUR2NMUR1OPRK1OPRM1 | |
| SCHEMBL30498506 | 0.83 | EPHA2 (0.58) | NTSR2NTSR1SORT1NMUR2NMUR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12152182-B2 | Polymer nanoparticles for afterglow molecular imaging | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2024-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12152182-B2 | Polymer nanoparticles for afterglow molecular imaging | CD68, ALG1, MB | MAPK8 4657/4885MAPK9 3080/4885MAPK10 2449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.