Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAMP3 | O60896 | 12/20 | 0.44 |
| ▸ | CALCR | P30988 | 12/20 | 0.44 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.44 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31437202 | 0.92 | OPRM1 (0.46) | NMUR2NMUR1NTSR1OPRM1OPRK1 | |
| SCHEMBL31223770 | 0.91 | KEAP1 (0.44) | RAMP3CALCRNMUR2NMUR1NTSR1 | |
| SCHEMBL31437168 | 0.89 | RAMP3 (0.47) | RAMP3CALCRNMUR2NMUR1NTSR1 | |
| SCHEMBL31679150 | 0.87 | RAMP3 (0.47) | RAMP3CALCRNMUR2NMUR1OPRM1 | |
| SCHEMBL30918790 | 0.86 | NMUR2 (0.49) | RAMP3CALCRNMUR2NMUR1NTSR1 | |
| SCHEMBL30905097 | 0.84 | OPRM1 (0.42) | NMUR2NMUR1OPRM1OPRK1 | |
| SCHEMBL29905998 | 0.84 | KEAP1 (0.45) | RAMP3CALCRKEAP1 | |
| SCHEMBL30868648 | 0.84 | IL23R (0.43) | RAMP3CALCRNMUR2NMUR1 | |
| SCHEMBL14028315 | 0.84 | RAMP3 (0.46) | RAMP3CALCRKEAP1 | |
| SCHEMBL30868640 | 0.84 | NMUR2 (0.44) | RAMP3CALCRNMUR2NMUR1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12152182-B2 | Polymer nanoparticles for afterglow molecular imaging | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2024-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12152182-B2 | Polymer nanoparticles for afterglow molecular imaging | CD68, ALG1, MB | RAMP3 3628/4885CALCR 2374/4885NMUR2 1188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.