Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAMP3 | O60896 | 13/20 | 0.47 |
| ▸ | CALCR | P30988 | 13/20 | 0.47 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.46 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31437202 | 0.89 | OPRM1 (0.46) | NMUR2NMUR1MAPK8MAPK9MAPK10 | |
| SCHEMBL30957280 | 0.87 | RAMP3 (0.46) | RAMP3CALCR | |
| SCHEMBL30868651 | 0.87 | KEAP1 (0.44) | RAMP3CALCRNMUR2NMUR1 | |
| SCHEMBL31249463 | 0.87 | RAMP3 (0.44) | RAMP3CALCRNMUR2NMUR1OPRM1 | |
| SCHEMBL31437168 | 0.86 | RAMP3 (0.47) | RAMP3CALCRNMUR2NMUR1OPRM1 | |
| SCHEMBL14028315 | 0.84 | RAMP3 (0.46) | RAMP3CALCR | |
| SCHEMBL30868648 | 0.84 | IL23R (0.43) | RAMP3CALCRNMUR2NMUR1MAPK8 | |
| SCHEMBL30868640 | 0.84 | NMUR2 (0.44) | RAMP3CALCRNMUR2NMUR1MAPK8 | |
| SCHEMBL30868635 | 0.84 | KEAP1 (0.45) | RAMP3CALCR | |
| SCHEMBL29905998 | 0.84 | KEAP1 (0.45) | RAMP3CALCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250382639-A1 | DISRUPTING THE LINC COMPLEX FOR TREATING LAMINOPATHY | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2025-12-18 | — | — | US | disclosed |
| US-12404522-B2 | Disrupting the LINC complex for treating laminopathy | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2025-09-02 | — | — | US | disclosed |