SCHEMBL768992

SCHEMBL768992

Cc1c2nc(c(-c3ccccc3)c3ccc([nH]3)c(C)c3nc(c(-c4ccccc4)c4ccc1[nH]4)C=C3)C=C2

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 5/20 0.57
▸ TOP1 P11387 4/20 0.55
▸ STAT3 P40763 1/20 0.55
▸ STAT1 P42224 1/20 0.55
▸ CYCS P99999 3/20 0.54
▸ ABCG2 Q9UNQ0 1/20 0.49
▸ ENPP2 Q13822 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15943764 1.00 TERT (0.57) TERTTOP1STAT3STAT1CYCS
SCHEMBL29405434 0.91 TOP1 (0.64) TERTTOP1STAT3STAT1CYCS
SCHEMBL30136 0.91 TOP1 (0.64) TERTTOP1STAT3STAT1CYCS
SCHEMBL8014524 0.89 TOP1 (0.62) TERTTOP1STAT3STAT1CYCS
SCHEMBL7987113 0.89 TOP1 (0.62) TERTTOP1STAT3STAT1CYCS
SCHEMBL1313700 0.89 TOP1 (0.62) TERTTOP1STAT3STAT1CYCS
SCHEMBL991489 0.89 TOP1 (0.62) TERTTOP1STAT3STAT1CYCS
SCHEMBL8014529 0.89 TOP1 (0.62) TERTTOP1STAT3STAT1CYCS
SCHEMBL15085674 0.89 TOP1 (0.62) TERTTOP1STAT3STAT1CYCS
SCHEMBL9418767 0.89 TOP1 (0.62) TERTTOP1STAT3STAT1CYCS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9623123-B2 Fluorescent conjugated polymers with a bodipy-based backbone and uses thereof MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2017-04-18 — — US disclosed
US-9623123-B2 Fluorescent conjugated polymers with a bodipy-based backbone and uses thereof MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2017-04-18 — — US disclosed
US-20170014532-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF UNIV MICHIGAN TECH (US) 2017-01-19 — — US disclosed
US-20170014532-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF UNIV MICHIGAN TECH (US) 2017-01-19 — — US disclosed
US-9412949-B2 Fluorescent conjugated polymers with a bodipy-based backbone and uses thereof MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2016-08-09 — — US disclosed
US-8841428-B2 Polynucleotide nanomechanical device that acts as an artificial ribosome and translates DNA signals into polymer assembly instructions NEW YORK UNIVERSITY (US) 2014-09-23 — — US disclosed
US-20120070382-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2012-03-22 — — US disclosed
US-20080221315-A1 NUCLEIC ACID-BASED TRANSLATION SYSTEM AND METHOD FOR DECODING NUCLEIC ACID ENCRYPTED MESSAGE NEW YORK UNIVERSITY (US) 2008-09-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080221315-A1 NUCLEIC ACID-BASED TRANSLATION SYSTEM AND METHOD FOR DECODING NUCLEIC ACID ENCRYPTED MESSAGE NSUN3, RNMT, RNGTT TERT 980/4885TOP1 3901/4885STAT3 316/4885
US-20170014532-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF TLR3, TLR5, PARP15 TERT 1272/4885TOP1 1149/4885STAT3 3565/4885
US-20120070382-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF TLR3, TLR5, PARP15 TERT 1272/4885TOP1 1149/4885STAT3 3565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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