Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CHRNG | P07510 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | CHRND | Q07001 | 1/20 | 0.33 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | OGA | O60502 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25305763 | 1.00 | HTR2A (0.39) | HTR2AHTR2CSSTR4EGFRCHRNB4 | |
| SCHEMBL31618413 | 0.84 | SSTR4 (0.42) | SSTR4EGFRPDPK1OGA | |
| SCHEMBL25259343 | 0.73 | CHRNB2 (0.35) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL30527729 | 0.72 | CHEK1 (0.34) | EGFRCHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL25306038 | 0.72 | CHEK1 (0.34) | EGFRCHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL31654140 | 0.69 | HTR2C (0.46) | HTR2AHTR2CCHRNB4CHRNA3CHRNB2 | |
| SCHEMBL31581935 | 0.69 | HTR2C (0.46) | HTR2AHTR2CCHRNB4CHRNA3CHRNB2 | |
| SCHEMBL25308469 | 0.68 | HTR2A (0.38) | HTR2AHTR2CCHRNB4CHRNA3CHRNB2 | |
| SCHEMBL22122009 | 0.68 | HTR2A (0.38) | HTR2AHTR2CCHRNB4CHRNA3CHRNB2 | |
| SCHEMBL31250394 | 0.68 | HTR2A (0.38) | HTR2AHTR2CCHRNB4CHRNA3CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118804917-A | STAT modulators and uses thereof | 瑞克鲁迪克斯制药股份有限公司 | 2024-10-18 | — | — | CN | disclosed |