SCHEMBL31255680

SCHEMBL31255680

COc1ccc(C(=O)NC2CCN(CC3CCN(C(=O)OC(C)(C)C)CC3)CC2)cc1N1CCC(=O)NC1=O

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ HDAC4 P56524 1/20 0.42
▸ MCHR1 Q99705 2/20 0.41
▸ BRD4 O60885 1/20 0.41
▸ CRBN Q96SW2 1/20 0.41
▸ PDE4A P27815 1/20 0.40
▸ PDE4B Q07343 1/20 0.40
▸ PDE4C Q08493 1/20 0.40
▸ PDE4D Q08499 1/20 0.40
▸ USP2 O75604 1/20 0.40
▸ LMNA P02545 1/20 0.40
▸ ACHE P22303 1/20 0.40
▸ USP30 Q70CQ3 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31255654 0.88 SOS1 (0.43) CRBNPDE4APDE4BPDE4CPDE4D
SCHEMBL25583436 0.88 SOS1 (0.44) CRBNPDE4APDE4BPDE4CPDE4D
SCHEMBL31255358 0.86 MCHR1 (0.45) MCHR1ACHE
Trifluoroacetic Acid SCHEMBL31255438 0.83 ACHE (0.42) MCHR1ACHE
SCHEMBL30278930 0.82 PDE4A (0.45) CRBNPDE4APDE4BPDE4CPDE4D
SCHEMBL25935490 0.82 DRD2 (0.47) BRD4CRBN
SCHEMBL30984835 0.81 SOS1 (0.51) CRBNPDE4APDE4BPDE4CPDE4D
Trifluoroacetic Acid SCHEMBL31255415 0.81 SOS1 (0.43) CRBNPDE4APDE4BPDE4CPDE4D
SCHEMBL30278924 0.80 DRD2 (0.47) CRBN
SCHEMBL21409243 0.79 DRD2 (0.51) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720044-A1 AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD Beactica Therapeutics AB (SE) 2026-04-08 — — EP disclosed
WO-2024240840-A1 AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD BEACTICA THERAPEUTICS AB (SE) 2024-11-28 — — WO disclosed
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