Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | HRH2 | P25021 | 2/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KPNA2 | P52292 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28265661 | 0.76 | ADORA1 (0.55) | ADORA1KDM4EADORA2AKMT2AHRH3 | |
| SCHEMBL4416122 | 0.73 | ADORA1 (0.59) | ADORA1KDM4EADORA2AKMT2AHRH3 | |
| SCHEMBL28957216 | 0.71 | LMNA (0.44) | KDM4EKMT2AMAPTHPGDGAA | |
| SCHEMBL14358933 | 0.70 | HEXA (0.65) | ADORA1KDM4EDYRK1AALDH1A1MAPT | |
| SCHEMBL12495753 | 0.70 | HRH3 (0.63) | ADORA1ADORA2AKMT2AHRH3HRH2 | |
| SCHEMBL10508211 | 0.69 | ALDH1A1 (0.60) | ADORA1KDM4EKMT2AALDH1A1MAPT | |
| SCHEMBL979446 | 0.69 | ADORA1 (0.67) | ADORA1KDM4EADORA2AKMT2AHRH3 | |
| SCHEMBL30412772 | 0.69 | ADORA1 (0.67) | ADORA1KDM4EADORA2AKMT2AHRH3 | |
| SCHEMBL31339965 | 0.69 | KMT2A (0.71) | ADORA1KDM4EADORA2AKMT2AHRH3 | |
| SCHEMBL1892740 | 0.69 | ADORA2A (0.59) | ADORA1KDM4EADORA2AKMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4716531-A2 | HETEROCYCLIC COMPOUNDS AS NRAS INHIBITORS | Board of Regents, The University of Texas System (US) | 2026-04-01 | — | — | EP | disclosed |
| WO-2024243186-A2 | HETEROCYCLIC COMPOUNDS AS NRAS INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-11-28 | — | — | WO | disclosed |