Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.50 |
| ▸ | APLNR | P35414 | 3/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | CTSH | P09668 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 7/20 | 0.47 |
| ▸ | NPY4R | P50391 | 7/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.47 |
| ▸ | NPY1R | P25929 | 5/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | CALCR | P30988 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31257029 | 0.93 | F2 (0.48) | C5AR1F2CALCR | |
| SCHEMBL31256979 | 0.90 | MAPK8 (0.51) | MAPK8MAPK9MAPK10CXCR4NPY2R | |
| SCHEMBL30512749 | 0.89 | NPY2R (0.55) | C5AR1APLNRCXCR4NPY2RNPY4R | |
| SCHEMBL16212659 | 0.88 | C5AR1 (0.54) | C5AR1APLNRCTSLCTSSCTSK | |
| SCHEMBL30262103 | 0.88 | F2 (0.60) | MAPK8MAPK9MAPK10NPY2RNPY4R | |
| SCHEMBL30116695 | 0.88 | C5AR1 (0.57) | C5AR1APLNRNPY2RNPY4RNPY5R | |
| SCHEMBL30432474 | 0.87 | CALCR (0.53) | MAPK8MAPK9MAPK10NPY2RNPY4R | |
| SCHEMBL30442638 | 0.86 | F2 (0.51) | C5AR1APLNRMAPK8MAPK9MAPK10 | |
| SCHEMBL29429586 | 0.86 | NTSR1 (0.56) | C5AR1 | |
| SCHEMBL30441868 | 0.86 | F2 (0.52) | C5AR1APLNRMAPK8MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240352445-A1 | HUMANIZATION, AFFINITY MATURATION, AND OPTIMIZATION METHODS FOR PROTEINS AND ANTIBODIES | ABWIZ BIO, INC. | 2024-10-24 | — | — | US | disclosed |