SCHEMBL31258192

SCHEMBL31258192

[2H]c1[nH]c(=O)[nH]c(=O)c1CNCC(=O)O

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
GAA P10253 2/20 0.31
CYP3A4 P08684 1/20 0.30
PARP1 P09874 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL101944 0.84 LMNA (0.41) LMNASMN1; SMN2GAA
SCHEMBL7206108 0.73 CYP3A4 (0.33) LMNASMN1; SMN2GAACYP3A4
SCHEMBL104627 0.72 KMT2A (0.48) GAAPARP1
5-Bromouracil SCHEMBL639925 0.71 KMT2A (0.39) LMNASMN1; SMN2
SCHEMBL4371043 0.70 CRBN (0.40) LMNASMN1; SMN2
SCHEMBL28991875 0.68 GAA (0.46) LMNAGAA
SCHEMBL3798407 0.68 DAO (0.33)
SCHEMBL7599612 0.65 PARP1 (0.44) LMNAGAAPARP1
SCHEMBL1072904 0.65 LMNA (0.38) LMNASMN1; SMN2GAACYP3A4
SCHEMBL1227718 0.64 GAA (0.47) LMNASMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3488837-B1 ELECTROPORATION APPARATUS FOR PROVIDING AGENTS TO THE COCHLEA NEWSOUTH INNOVATIONS PTY LTD (AU) 2024-11-27 EP disclosed