SCHEMBL3798407

SCHEMBL3798407

O=C(O)CNCc1cn(S)c(=O)[nH]c1=O

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.33
PDCD1 Q15116 1/20 0.31
CD274 Q9NZQ7 1/20 0.31
APEX1 P27695 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL453314 0.71 DNPH1 (0.48)
SCHEMBL101944 0.70 LMNA (0.41)
SCHEMBL18503558 0.69 PYGM (0.58)
SCHEMBL14853731 0.69 PYGM (0.58)
SCHEMBL18512960 0.69 PYGM (0.58)
SCHEMBL63573 0.69 PYGM (0.58)
SCHEMBL41270 0.69 PYGM (0.58)
SCHEMBL18573807 0.69 PYGM (0.58)
SCHEMBL18464475 0.69 PYGM (0.49)
SCHEMBL104627 0.68 KMT2A (0.48) PDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2193373-A1 METHODS AND KITS FOR MEASURING VON WILLEBRAND FACTOR Bloodcenter Of Wisconsin, Inc. (US) 2010-06-09 EP disclosed
WO-2009026551-A1 METHODS AND KITS FOR MEASURING VON WILLEBRAND FACTOR BLOODCENTER OF WISCONSIN, INC. (US) 2009-02-26 WO disclosed