Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.48 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.48 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 2/20 | 0.44 |
| ▸ | TYK2 | P29597 | 2/20 | 0.44 |
| ▸ | JAK3 | P52333 | 2/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | RET | P07949 | 2/20 | 0.44 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19823045 | 0.84 | TNIK (0.54) | OPRM1CAMKK2TNIKDRD2HTR2A | |
| SCHEMBL19823067 | 0.76 | TNIK (0.68) | TNIKKCNH2RETROCK2ABL1 | |
| SCHEMBL19823044 | 0.76 | LRRK2 (0.59) | OPRM1CAMKK2TNIKDRD2HTR2A | |
| SCHEMBL31358111 | 0.76 | OPRM1 (0.58) | OPRM1KCNH2JAK2TYK2JAK3 | |
| SCHEMBL19823109 | 0.76 | TNIK (0.53) | OPRM1CAMKK2TNIKDRD2HTR2A | |
| SCHEMBL4471272 | 0.75 | CNR2 (0.71) | CNR2DRD2HTR2AHTR2CKCNH2 | |
| SCHEMBL19823048 | 0.75 | TNIK (0.52) | OPRM1CAMKK2TNIKDRD2HTR2A | |
| SCHEMBL19823047 | 0.75 | TNIK (0.49) | OPRM1CAMKK2TNIKDRD2HTR2A | |
| SCHEMBL28226193 | 0.73 | CYP1A2 (0.66) | CNR2DRD2HTR2AHTR2CKCNH2 | |
| SCHEMBL21044844 | 0.72 | CAMKK2 (0.54) | CAMKK2TNIKJAK2TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240391896-A1 | SMALL MOLECULE COMPOUND TARGETING BCL9/BETA-CATENIN INTERACTION | Nantong Jutai Biotech Co., Ltd. (CN) | 2024-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240391896-A1 | SMALL MOLECULE COMPOUND TARGETING BCL9/BETA-CATENIN INTERACTION | BCL9, BCL9L, BCL2L11 | CNR2 4171/4885OPRM1 4604/4885CAMKK2 791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.