SCHEMBL3125873

SCHEMBL3125873

Nc1c(O)cccc1C(=O)c1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
G6PD P11413 1/20 0.66
CASP7 P55210 1/20 0.66
CASP6 P55212 1/20 0.66
GAA P10253 2/20 0.60
MAPT P10636 1/20 0.60
AKR1C3 P42330 1/20 0.53
LIG1 P18858 1/20 0.53
MEN1 O00255 2/20 0.50
USP2 O75604 2/20 0.50
KMT2A Q03164 2/20 0.50
KDM4E B2RXH2 1/20 0.50
HIF1A Q16665 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
KEAP1 Q14145 1/20 0.50
NFE2L2 Q16236 1/20 0.50
ALDH1A1 P00352 2/20 0.49
LMNA P02545 1/20 0.49
GLA P06280 1/20 0.49
HSD17B10 Q99714 1/20 0.49
PBRM1 Q86U86 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL717462 0.86 G6PD (0.72) G6PDCASP7CASP6GAAMAPT
SCHEMBL11160377 0.84 G6PD (0.64) G6PDCASP7CASP6GAAMAPT
Benzene SCHEMBL28303083 0.82 MAPT (0.74) GAAMAPTAKR1C3MEN1USP2
SCHEMBL29786713 0.82 MAPT (0.74) GAAMAPTAKR1C3MEN1USP2
SCHEMBL2690787 0.82 AKR1C3 (0.67) G6PDCASP7CASP6GAAMAPT
SCHEMBL112508 0.82 MAPT (0.74) GAAMAPTAKR1C3MEN1USP2
Benzene SCHEMBL6034371 0.81 LIG1 (0.76) GAAMAPTAKR1C3LIG1MEN1
SCHEMBL29390505 0.81 LIG1 (0.76) GAAMAPTAKR1C3LIG1MEN1
SCHEMBL22129808 0.81 LIG1 (0.76) GAAMAPTAKR1C3LIG1MEN1
SCHEMBL36215 0.81 LIG1 (0.76) GAAMAPTAKR1C3LIG1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102573772-A Cosmetic compositions comprising an ester derived from 4-carboxy-2-pyrrolidinone and a lipophilic screening agent OREAL 2012-07-11 CN claimed
CN-101406434-A Fragrance composition comprising the combination of one filter a hydroxyaminobenzophenone, one filter b cinnamate and of one compound c piperidinole, benzotriazole or dibenzoylmethane OREAL (FR) 2009-04-15 CN claimed
CN-1937992-A Use of benzophenone uv filters for preventing tanning CIBA SC HOLDING AG (CH) 2007-03-28 CN claimed
CN-105358123-B UV screening composition comprising a UV filter, an organopolysiloxane functionalized with a UV absorber, and porous silica and/or polymethylmethacrylate particles 帝斯曼知识产权资产管理有限公司 2018-11-13 CN disclosed
CN-105307631-B Include the cosmetics or dermatological compositions of the UVA- smoke agents for shielding and/or the organic UVA- smoke agents for shielding of hydrophily of merocyanine and the 2- dihydroxy benaophenonel types of amino substitution 莱雅公司 2018-09-18 CN disclosed
CN-107260561-A Cosmetic and/or dermatological composition containing merocyanine derivatives 莱雅公司 2017-10-20 CN disclosed
CN-103917218-B Cosmetic and/or dermatological compositions containing merocyanine derivatives comprising specific polar groups constituted by hydroxyl-and ether-functional groups 莱雅公司 2017-06-09 CN disclosed
CN-105358123-A UV screening composition comprising a UV filter, an organopolysiloxane functionalized with a UV absorber, and porous silica and/or polymethylmethacrylate particles DSM IP ASSETS BV 2016-02-24 CN disclosed
CN-105307631-A Cosmetic or dermatological composition comprising a merocyanine and a uva-screening agent of the amino-substituted 2-hydroxybenzophenone type and/or a hydrophilic organic uva-screening agent OREAL 2016-02-03 CN disclosed
CN-102232093-B New method DSM IP ASSETS BV 2014-09-03 CN disclosed
CN-103917218-A Cosmetic and/or dermatological compositions containing merocyanine derivatives comprising specific polar groups constituted by hydroxyl-and ether-functional groups OREAL 2014-07-09 CN disclosed
CN-1678284-A Dyeing method for porous material CIBA SC HOLDING AG (CH) 2005-10-05 CN disclosed
CN-1678285-A Dyeing method for porous material CIBA SC HOLDING AG (CH) 2005-10-05 CN disclosed
CN-1665475-A Merocyanine derivatives for cosmetic use CIBA SC HOLDING AG (CH) 2005-09-07 CN disclosed
CN-1646507-A Aminophenylbenzothiazole compounds CIBA SC HOLDING AG (CH) 2005-07-27 CN disclosed
CN-1646091-A Organosilicone derivatives of amino hydroxybenzophenones and their use as UV-A filters in cosmetic preparations DSM IP ASSETS BV (NL) 2005-07-27 CN disclosed
CN-1642522-A Uv absorber compositions comprising a hydroxyphenyltriazine compound CIBA SC HOLDING AG (CH) 2005-07-20 CN disclosed
CN-1615343-A Yellow cationic dyes for dying of organic material CIBA SC HOLDING AG (CH) 2005-05-11 CN disclosed
CN-1556839-A Cationic reactive dyes 西巴特殊化学品控股有限公司 2004-12-22 CN disclosed
CN-1324610-A Use of sunblock composition using aminohydrox-diphenyl methanone as necessary components in light-stabilizing UV filtering agent, in cosmetics and medicines BASF AG (DE) 2001-12-05 CN disclosed