Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.52 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.50 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.50 |
| ▸ | ITGAL | P20701 | 1/20 | 0.50 |
| ▸ | P4HB | P07237 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22322144 | 1.00 | ERAP2 (0.52) | ERAP2P2RY14ALOX15ACEMEN1 | |
| SCHEMBL2934308 | 1.00 | ERAP2 (0.52) | ERAP2P2RY14ALOX15ACEMEN1 | |
| SCHEMBL17848778 | 0.91 | ACE (0.54) | ERAP2P2RY14ALOX15ACEMEN1 | |
| SCHEMBL5805740 | 0.91 | ACE (0.54) | ERAP2P2RY14ALOX15ACEMEN1 | |
| SCHEMBL8525238 | 0.88 | MEN1 (0.57) | ERAP2P2RY14ALOX15ACEMEN1 | |
| SCHEMBL5281197 | 0.88 | MEN1 (0.57) | ERAP2P2RY14ALOX15ACEMEN1 | |
| Tryptamine SCHEMBL13278244 | 0.86 | MPO (0.52) | ERAP2P2RY14ALOX15ACEMEN1 | |
| SCHEMBL3344871 | 0.85 | MC4R (0.55) | ERAP2P2RY14ALOX15ACEITGB2 | |
| SCHEMBL7271569 | 0.85 | MC4R (0.55) | ERAP2P2RY14ALOX15ACEITGB2 | |
| SCHEMBL13278205 | 0.84 | ALOX15 (0.70) | ERAP2P2RY14ALOX15ACEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024243289-A2 | GUT MICROBE DERIVED AROMATIC AMINO ACID METABOLITES FOR DETECTION AND TREATMENT OF DISEASE | THE CLEVELAND CLINIC FOUNDATION (US) | 2024-11-28 | — | — | WO | claimed |
| WO-2024243289-A2 | GUT MICROBE DERIVED AROMATIC AMINO ACID METABOLITES FOR DETECTION AND TREATMENT OF DISEASE | THE CLEVELAND CLINIC FOUNDATION (US) | 2024-11-28 | — | — | WO | disclosed |