Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 3/20 | 0.55 |
| ▸ | MC1R | Q01726 | 1/20 | 0.55 |
| ▸ | MC5R | P33032 | 2/20 | 0.51 |
| ▸ | MC3R | P41968 | 2/20 | 0.51 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.51 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.50 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.50 |
| ▸ | ITGAL | P20701 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | GHSR | Q92847 | 1/20 | 0.49 |
| ▸ | P4HB | P07237 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7271569 | 1.00 | MC4R (0.55) | MC4RMC1RMC5RMC3RERAP2 | |
| SCHEMBL9752019 | 0.89 | ALDH1A1 (0.58) | MC4RMC1RMC5RMC3R | |
| SCHEMBL1129962 | 0.89 | P2RY14 (0.53) | ERAP2P2RY14ACEITGB2ICAM1 | |
| SCHEMBL4745190 | 0.87 | P2RY14 (0.54) | ERAP2P2RY14ACEALOX15P4HB | |
| SCHEMBL5809845 | 0.86 | MC4R (0.47) | MC4RMC1RMC5RMC3RERAP2 | |
| SCHEMBL2934308 | 0.85 | ERAP2 (0.52) | ERAP2P2RY14ACEITGB2ICAM1 | |
| SCHEMBL22322144 | 0.85 | ERAP2 (0.52) | ERAP2P2RY14ACEITGB2ICAM1 | |
| SCHEMBL31258750 | 0.85 | ERAP2 (0.52) | ERAP2P2RY14ACEITGB2ICAM1 | |
| Tryptamine SCHEMBL13278244 | 0.85 | MPO (0.52) | ERAP2P2RY14ACEITGB2ICAM1 | |
| SCHEMBL17848778 | 0.85 | ACE (0.54) | ERAP2P2RY14ACEITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093538-A1 | Pseudomonas Bacterium | NOVOZYMES A/S (DK) | 2010-04-15 | — | — | US | disclosed |
| WO-2010037072-A1 | PSEUDOMONAS BACTERIUM | NOVOZYMES A/S (DK) | 2010-04-01 | — | — | WO | disclosed |
| EP-0528312-A2 | Cyclic peptides and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |