Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24599026 | 0.83 | HDAC1 (0.55) | KMT2ANPC1RAB9ANAMPTLMNA | |
| SCHEMBL1424897 | 0.77 | ACACB (0.45) | APLNRGAAKMT2AMEN1NPC1 | |
| SCHEMBL30015957 | 0.77 | LMNA (0.43) | APLNRNAMPTLMNAPOLB | |
| SCHEMBL28645962 | 0.77 | LMNA (0.43) | APLNRNAMPTLMNAPOLB | |
| SCHEMBL17172491 | 0.77 | ALDH1A1 (0.66) | GAAKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22288616 | 0.76 | HDAC6 (0.39) | APLNRNPC1RAB9ALMNAPOLB | |
| SCHEMBL25659553 | 0.75 | CA12 (0.40) | NFKB1NFKB2RELAGABRA5ALDH1A1 | |
| SCHEMBL109898 | 0.75 | SMYD3 (0.39) | APLNRGAAKMT2AMEN1NPC1 | |
| SCHEMBL3842089 | 0.75 | SMN1; SMN2 (0.56) | GAAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL1477613 | 0.75 | MIF (0.50) | GAAKMT2AMEN1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250171433-A1 | A1H-BENZO[C][1,2]THIADIAZINE-2,2-DIOXIDES BEARING HETEROCYCLIC LINKERS AS SELECTIVE HISTONE DEACETYLASE 6 INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2025-05-29 | — | — | US | disclosed |
| CN-118973573-A | 1H-benzo [ c ] [1,2] thiadiazine-2, 2-dioxides carrying a heterocyclic linker as selective histone deacetylase 6 inhibitors | 乔治城大学 | 2024-11-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250171433-A1 | A1H-BENZO[C][1,2]THIADIAZINE-2,2-DIOXIDES BEARING HETEROCYCLIC LINKERS AS SELECTIVE HISTONE DEACETYLASE 6 INHIBITORS | HDAC1, HDAC6, HDAC11 | APLNR 4070/4885GAA 1347/4885KMT2A 73/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.