Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.43 |
| ▸ | PIM1 | P11309 | 3/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.41 |
| ▸ | NUAK1 | O60285 | 2/20 | 0.41 |
| ▸ | IGF1R | P08069 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | PLK1 | P53350 | 2/20 | 0.41 |
| ▸ | PKN1 | Q16512 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | NEK2 | P51955 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | NEK6 | Q9HC98 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31259502 | 0.82 | POLH (0.46) | POLHALOX5PIM1KDRNUAK1 | |
| SCHEMBL22244160 | 0.71 | POLH (0.50) | POLHALOX5PIM1KDRNUAK1 | |
| SCHEMBL13552041 | 0.71 | MEN1 (0.76) | POLHALOX5PIM1KDRNUAK1 | |
| SCHEMBL12557415 | 0.70 | POLH (0.62) | POLHALOX5PIM1KDRNUAK1 | |
| SCHEMBL9565912 | 0.70 | POLH (0.65) | POLHALOX5PIM1KDRNUAK1 | |
| SCHEMBL16682483 | 0.69 | POLH (0.77) | POLHALOX5PIM1KDRNUAK1 | |
| SCHEMBL12557413 | 0.69 | POLH (0.50) | POLHALOX5PIM1KDRNUAK1 | |
| SCHEMBL25734128 | 0.68 | POLH (0.49) | POLHALOX5ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL10665463 | 0.67 | CYP3A4 (0.55) | POLHALOX5PIM1ALDH1A1CYP3A4 | |
| SCHEMBL29158205 | 0.67 | CYP3A4 (0.62) | POLHALOX5KDRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118834192-A | 4' -Hydroxy-3, 5, 7, 3', 5' -pentamethoxyl flavone, enzymatic biosynthesis, separation preparation method and lipid-lowering activity improvement research | 江南大学 | 2024-10-25 | — | — | CN | disclosed |