Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 4/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | FTO | Q9C0B1 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | XDH | P47989 | 4/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.59 |
| ▸ | CA12 | O43570 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30819258 | 0.90 | POLH (0.80) | POLHCYP3A4ABCB1CYP2D6CYP2C9 | |
| SCHEMBL6140182 | 0.90 | POLH (0.80) | POLHCYP3A4ABCB1CYP2D6CYP2C9 | |
| SCHEMBL14769773 | 0.89 | MEN1 (0.76) | POLHCYP3A4ABCB1CYP2D6CYP2C9 | |
| SCHEMBL12557415 | 0.86 | POLH (0.62) | POLHCYP3A4ABCB1CYP2D6CYP2C9 | |
| SCHEMBL23919099 | 0.81 | MEN1 (0.65) | POLHCYP3A4ABCB1CYP2D6CYP2C9 | |
| SCHEMBL9733297 | 0.81 | ABCB1 (0.76) | POLHCYP3A4ABCB1CYP2D6CYP2C9 | |
| SCHEMBL12636895 | 0.80 | CYP3A4 (0.74) | POLHCYP3A4ABCB1CYP2D6CYP2C9 | |
| SCHEMBL824468 | 0.79 | POLH (1.00) | POLHCYP3A4ABCB1CYP2D6CYP2C9 | |
| SCHEMBL18130383 | 0.79 | ALOX5 (0.62) | POLHCYP3A4ABCB1CYP2D6MEN1 | |
| SCHEMBL12919332 | 0.78 | POLH (0.70) | POLHCYP3A4ABCB1CYP2D6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548798-A1 | Antiviral agent | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |