Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14789897 | 1.00 | CYP11B1 (0.48) | CYP11B1CYP11B2CYP1A2GAACYP2C9 | |
| SCHEMBL31260099 | 0.84 | CYP11B2 (0.45) | CYP11B1CYP11B2CYP1A2GAATSHR | |
| SCHEMBL14792915 | 0.84 | CYP11B2 (0.45) | CYP11B1CYP11B2CYP1A2GAATSHR | |
| SCHEMBL31260010 | 0.82 | CYP11B1 (0.53) | CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL14789837 | 0.82 | CYP11B1 (0.53) | CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL21518692 | 0.78 | CYP11B1 (0.62) | CYP11B1CYP11B2CYP1A2CYP2C9TBXAS1 | |
| SCHEMBL31260033 | 0.75 | CYP11B2 (0.58) | CYP11B1CYP11B2CYP1A2CYP2C9TBXAS1 | |
| SCHEMBL14789896 | 0.75 | CYP11B2 (0.58) | CYP11B1CYP11B2CYP1A2CYP2C9TBXAS1 | |
| SCHEMBL14778457 | 0.74 | CYP11B1 (0.62) | CYP11B1CYP11B2CYP1A2CYP2C9TBXAS1 | |
| SCHEMBL31259949 | 0.74 | CYP11B2 (0.57) | CYP11B1CYP11B2CYP1A2CYP2C9TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653618-B1 | NEW DIHYDROQUINOLINE-2-ONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2025-01-08 | — | — | EP | disclosed |