Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.32 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17839887 | 0.78 | NLRP3 (0.39) | SMN1; SMN2NLRP3PDGFRACDK5TYRO3 | |
| SCHEMBL17802138 | 0.70 | PDGFRA (0.38) | SMN1; SMN2PDGFRACDK5TYRO3F2 | |
| SCHEMBL29985546 | 0.70 | PDGFRA (0.38) | SMN1; SMN2PDGFRACDK5TYRO3F2 | |
| SCHEMBL26619479 | 0.67 | SMN1; SMN2 (0.41) | SMN1; SMN2NLRP3ELANEMEN1LMNA | |
| SCHEMBL22151999 | 0.66 | AR (0.35) | SMN1; SMN2PDGFRACDK5TYRO3F2 | |
| SCHEMBL19896301 | 0.65 | OXER1 (0.33) | SMN1; SMN2PDGFRACDK5TYRO3OXER1 | |
| SCHEMBL22155667 | 0.64 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1LMNAHTTKMT2A | |
| SCHEMBL23993144 | 0.64 | ESR1 (0.41) | PDGFRACDK5TYRO3ELANE | |
| SCHEMBL17673189 | 0.62 | CREBBP (0.40) | SMN1; SMN2F2PLAUELANECTRB1 | |
| SCHEMBL923650 | 0.61 | DNM1 (0.37) | SMN1; SMN2MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118804911-A | Acrylamide compound | NRG治疗有限公司 | 2024-10-18 | — | — | CN | disclosed |