Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL143872 | 1.00 | KDM4E (0.46) | KDM4EPOLBL3MBTL1NQO2ALDH1A1 | |
| SCHEMBL25360994 | 0.85 | KDM4E (0.54) | KDM4EPOLBL3MBTL1NQO2ALDH1A1 | |
| SCHEMBL26040458 | 0.83 | NQO2 (0.46) | KDM4EPOLBL3MBTL1NQO2ALDH1A1 | |
| SCHEMBL25208528 | 0.83 | KDM4E (0.44) | KDM4EPOLBL3MBTL1NQO2ALDH1A1 | |
| SCHEMBL536169 | 0.83 | KDM4E (0.50) | KDM4EPOLBNQO2ALDH1A1GAA | |
| SCHEMBL17840704 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1GAAHSD17B10TSHR | |
| SCHEMBL5203594 | 0.81 | L3MBTL1 (0.43) | KDM4EL3MBTL1ALDH1A1GAAHPGD | |
| SCHEMBL17840559 | 0.80 | SMN1; SMN2 (0.41) | KDM4EALDH1A1HPGDHSD17B10CFTR | |
| SCHEMBL535621 | 0.78 | KDM4E (0.41) | KDM4EPOLBL3MBTL1ALDH1A1GAA | |
| SCHEMBL16336369 | 0.77 | ABL1 (0.45) | KDM4EL3MBTL1NQO2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025007915-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2025-01-09 | — | — | WO | disclosed |
| CN-119264042-A | Cyclopentane derivative-containing inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2025-01-07 | — | — | CN | disclosed |