Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL143872 | 0.85 | KDM4E (0.46) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL31264183 | 0.85 | KDM4E (0.46) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL31310191 | 0.83 | KDM4E (0.56) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL25208528 | 0.82 | KDM4E (0.44) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL536169 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL25361675 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL31752906 | 0.80 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10BACE1 | |
| SCHEMBL26040460 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL31447500 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL17201206 | 0.76 | KDM4E (0.47) | KDM4EALDH1A1HPGDPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072265-A1 | SOMATOSTATIN SUBTYPE RECEPTOR 3 (SSTR3) AGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2025-04-03 | — | — | WO | disclosed |
| WO-2023159155-A1 | INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) AND USES THEREOF | PIVALENT THERAPEUTICS, INC. (US) | 2023-08-24 | — | — | WO | disclosed |