Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 9/20 | 0.36 |
| ▸ | SRC | P12931 | 6/20 | 0.36 |
| ▸ | KDR | P35968 | 6/20 | 0.36 |
| ▸ | ABL1 | P00519 | 5/20 | 0.36 |
| ▸ | EGFR | P00533 | 5/20 | 0.36 |
| ▸ | HCK | P08631 | 5/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.36 |
| ▸ | MTOR | P42345 | 4/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31264634 | 0.85 | CYP3A4 (0.43) | CYP2C9CYP2C19CYP3A4CYP2D6FGFR1 | |
| SCHEMBL31264736 | 0.81 | EIF2AK3 (0.44) | SRCKDRLCKTEKRIPK2 | |
| SCHEMBL22658735 | 0.79 | CYP3A4 (0.64) | CYP2C9CYP2C19CYP3A4CYP2D6FGFR1 | |
| SCHEMBL31264707 | 0.77 | CYP3A4 (0.43) | CYP2C9CYP2C19CYP3A4CYP2D6FGFR1 | |
| SCHEMBL31264720 | 0.76 | CYP3A4 (0.51) | CYP2C9CYP2C19CYP3A4CYP2D6FGFR1 | |
| SCHEMBL31264741 | 0.76 | CYP3A4 (0.51) | CYP2C9CYP2C19CYP3A4CYP2D6FGFR1 | |
| SCHEMBL31264680 | 0.76 | FGFR1 (0.60) | CYP2C9CYP2C19CYP3A4CYP2D6FGFR1 | |
| SCHEMBL24458871 | 0.75 | RET (0.47) | PIK3CDSRCKDRABL1EGFR | |
| SCHEMBL31264711 | 0.73 | FGFR1 (0.43) | CYP2C9CYP2C19CYP3A4CYP2D6FGFR1 | |
| SCHEMBL31264649 | 0.73 | FGFR1 (0.43) | CYP2C9CYP2C19CYP3A4CYP2D6FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4722216-A1 | PYRROLOPYRIMIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | Kangbaida (Sichuan) Biotechnology Co., Ltd. (CN) | 2026-04-08 | — | — | EP | disclosed |
| CN-119894900-A | Pyrrolo pyrimidine derivative and application thereof in medicine | 康百达（四川）生物医药科技有限公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024251147-A1 | PYRROLOPYRIMIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | 康百达（四川）生物医药科技有限公司 | 2024-12-12 | — | — | WO | disclosed |