SCHEMBL31265506

CSCC[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	CALCR	P30988	3/20	0.60

▸	CRHR1	P34998	1/20	0.59

▸	CRHR2	Q13324	1/20	0.59

▸	GLP1R	P43220	10/20	0.57

▸	SCTR	P47872	1/20	0.57

▸	CCKBR	P32239	1/20	0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29880436	0.97	CALCR (0.60)	CALCRCRHR1CRHR2GLP1RSCTR
SCHEMBL29726691	0.97	CALCR (0.60)	CALCRCRHR1CRHR2GLP1RSCTR
SCHEMBL30778184	0.97	CALCR (0.60)	CALCRCRHR1CRHR2GLP1RSCTR
SCHEMBL29994110	0.95	CALCR (0.58)	CALCRCRHR1CRHR2GLP1RSCTR
SCHEMBL29682931	0.92	GLP1R (0.65)	CALCRGLP1RSCTRCCKBR
SCHEMBL31139948	0.92	GLP1R (0.66)	GLP1RSCTRCCKBR
SCHEMBL30427404	0.92	CRHR1 (0.66)	CALCRCRHR1CRHR2GLP1RSCTR
SCHEMBL31243560	0.92	CALCR (0.59)	CALCRCRHR1CRHR2GLP1RCCKBR
SCHEMBL30387584	0.91	GLP1R (0.65)	CALCRGLP1RSCTRCCKBR
SCHEMBL29378700	0.91	CALCR (0.54)	CALCRCRHR1CRHR2GLP1RSCTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-119876131-A	GLP-1 receptor ligand moiety conjugated oligonucleotides and uses thereof	IONIS制药公司	2025-04-25	—	—	CN	disclosed
CN-111448207-B	GLP-1 receptor ligand moiety conjugated oligonucleotides and uses thereof	IONIS制药公司	2024-11-01	—	—	CN	disclosed