Sugi Predict

Sugi Predict / Compounds / SCHEMBL29378700

SCHEMBL29378700

SCHEMBL29378700

CSCC[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CALCR P30988 3/20 0.54
▸ CRHR1 P34998 1/20 0.53
▸ CRHR2 Q13324 1/20 0.53
▸ GLP1R P43220 13/20 0.52
▸ SCTR P47872 1/20 0.52
▸ GCGR P47871 4/20 0.49
▸ PTH1R Q03431 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29994110 0.95 CALCR (0.58) CALCRCRHR1CRHR2GLP1RSCTR
SCHEMBL29726691 0.94 CALCR (0.60) CALCRCRHR1CRHR2GLP1RSCTR
SCHEMBL30778184 0.94 CALCR (0.60) CALCRCRHR1CRHR2GLP1RSCTR
SCHEMBL29880436 0.94 CALCR (0.60) CALCRCRHR1CRHR2GLP1RSCTR
SCHEMBL30358158 0.92 CALCR (0.57) CALCRCRHR1CRHR2GLP1RSCTR
SCHEMBL31265506 0.91 CALCR (0.60) CALCRCRHR1CRHR2GLP1RSCTR
SCHEMBL30567705 0.89 CALCR (0.65) CALCRCRHR1CRHR2GLP1RSCTR
SCHEMBL30974478 0.89 GLP1R (0.49) CALCRCRHR1CRHR2GLP1RSCTR
SCHEMBL31139979 0.88 GLP1R (0.66) GLP1RSCTRGCGR
SCHEMBL29777814 0.88 CALCR (0.51) CALCRCRHR1CRHR2GLP1RSCTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109310727-B Conditionally active heterodimeric polypeptides and methods of use thereof 加利福尼亚大学董事会 2022-09-27 — — CN claimed
CN-116334113-A Conditionally active heterodimeric polypeptides and methods of use thereof 加利福尼亚大学董事会 2023-06-27 — — CN disclosed
CN-113651870-B Small molecule modified short peptide for promoting tissue repair and regeneration after trauma and application thereof 暨南大学 2023-06-13 — — CN disclosed
CN-109310727-B Conditionally active heterodimeric polypeptides and methods of use thereof 加利福尼亚大学董事会 2022-09-27 — — CN disclosed
US-20220213452-A1 CONDITIONALLY ACTIVE HETERODIMERIC POLYPEPTIDES AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-07-07 — — US disclosed
US-20220041687-A1 A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) ST. ANNA KINDERKREBSFORSCHUNG (AT) 2022-02-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220041687-A1 A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) CARS1, CD74, HAVCR2 CALCR 625/4885CRHR1 903/4885CRHR2 1133/4885
US-20220213452-A1 CONDITIONALLY ACTIVE HETERODIMERIC POLYPEPTIDES AND METHODS OF USE THEREOF CPB2, AGBL2, IAPP CALCR 2590/4885CRHR1 3032/4885CRHR2 1902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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