Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25324267 | 1.00 | ERN1 (0.35) | ERN1TRIM24TRIM33 | |
| SCHEMBL22542733 | 0.70 | LMNA (0.41) | ERN1TRIM24TRIM33 | |
| SCHEMBL31087530 | 0.70 | LMNA (0.41) | ERN1TRIM24TRIM33 | |
| SCHEMBL11544210 | 0.69 | HTT (0.35) | — | |
| SCHEMBL23164345 | 0.68 | TRIM24 (0.47) | ERN1TRIM24TRIM33 | |
| SCHEMBL29463667 | 0.68 | TRIM24 (0.47) | ERN1TRIM24TRIM33 | |
| SCHEMBL25342803 | 0.66 | ERN1 (0.41) | ERN1 | |
| SCHEMBL567898 | 0.65 | CCNC (0.34) | ERN1 | |
| SCHEMBL6900813 | 0.65 | ERN1 (0.45) | ERN1 | |
| SCHEMBL22366841 | 0.65 | MEN1 (0.37) | TRIM24TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119060035-A | Nitrogen-containing polycyclic derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-12-03 | — | — | CN | disclosed |