Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22542733 | 1.00 | LMNA (0.41) | LMNAKDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL22542665 | 0.80 | ALDH1A1 (0.39) | LMNAKDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL19870692 | 0.76 | KDM4E (0.41) | LMNAKDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL25342803 | 0.75 | ERN1 (0.41) | LMNAALDH1A1HPGDERN1PRKDC | |
| SCHEMBL11207268 | 0.74 | NPC1 (0.31) | KDM4EALDH1A1 | |
| SCHEMBL2877344 | 0.70 | LMNA (0.37) | LMNA | |
| SCHEMBL25324267 | 0.70 | ERN1 (0.35) | TRIM24TRIM33ERN1 | |
| SCHEMBL31266464 | 0.70 | ERN1 (0.35) | TRIM24TRIM33ERN1 | |
| SCHEMBL18613842 | 0.69 | PRKDC (0.38) | LMNAKDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL19965792 | 0.68 | ERN1 (0.32) | LMNAKDM4EMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118591541-A | Substituted bicyclic heterocycles as MALT-1 inhibitors | 奥瑞基尼肿瘤有限公司 | 2024-09-03 | — | — | CN | disclosed |