Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 5/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL149899 | 1.00 | MAPK1 (0.56) | MAPK1MTNR1AMTNR1BMAOBNPSR1 | |
| SCHEMBL146017 | 0.91 | MAPK1 (0.54) | MAPK1MTNR1AMTNR1BMAOBNPSR1 | |
| SCHEMBL22367610 | 0.91 | ALDH1A1 (0.44) | MAPK1MTNR1AMTNR1BTSHRL3MBTL1 | |
| SCHEMBL146567 | 0.90 | MAPK1 (0.53) | MAPK1MTNR1AMTNR1BMAOBNPSR1 | |
| Allylanisole SCHEMBL28023200 | 0.84 | DRD2 (0.53) | TSHRL3MBTL1MEN1CYP1A2CYP3A4 | |
| SCHEMBL1729519 | 0.82 | MAPK1 (0.75) | MAPK1MTNR1AMTNR1BMAOBNPSR1 | |
| SCHEMBL19287147 | 0.82 | MAPK1 (0.56) | MAPK1MTNR1AMTNR1BMAOBNPSR1 | |
| SCHEMBL10187327 | 0.82 | HPGD (0.56) | MAPK1LMNAL3MBTL1KMT2AHSD17B10 | |
| SCHEMBL123591 | 0.81 | MAOB (0.53) | MAPK1MTNR1AMTNR1BMAOBLMNA | |
| SCHEMBL17138189 | 0.81 | ALDH1A1 (0.51) | MAPK1TSHRL3MBTL1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688743-A1 | INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY | University of Virginia Patent Foundation (US) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024206153-A1 | INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2024-10-03 | — | — | WO | disclosed |