Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520719 | 0.90 | MEN1 (0.50) | LMNAALDH1A1GAAMAPTKDM4E | |
| SCHEMBL3388748 | 0.85 | TP53 (0.53) | LMNAMAPK1TSHRALDH1A1GAA | |
| SCHEMBL5355917 | 0.85 | CA12 (0.55) | LMNATSHRALDH1A1GAAMAPT | |
| SCHEMBL22215904 | 0.84 | MEN1 (0.47) | LMNAALDH1A1GAAMAPTKDM4E | |
| SCHEMBL6695861 | 0.84 | ALDH1A1 (0.50) | MAOBLMNATSHRALDH1A1GAA | |
| SCHEMBL1986202 | 0.82 | MAOB (0.55) | MAOBLMNAMAPK1APPTSHR | |
| Anisole SCHEMBL28165406 | 0.82 | CA4 (0.56) | MAOBTSHRALDH1A1GAAMAPT | |
| SCHEMBL2844342 | 0.81 | KMT2A (0.50) | LMNAMAPK1TSHRALDH1A1GAA | |
| SCHEMBL10904568 | 0.81 | MAOB (0.50) | MAOBLMNAMAPK1APPTSHR | |
| SCHEMBL149899 | 0.81 | MAPK1 (0.56) | MAOBLMNAMAPK1APPTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239774-A1 | SOLUBLE ADENYLYL CYCLASE (SAC) INHIBITORS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2024-07-18 | — | — | US | disclosed |
| CN-114481405-B | Composite fiber textile fabric | 南通德来利纺织有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-114481405-A | Composite fiber textile fabric | 南通德来利纺织有限公司 | 2022-05-13 | — | — | CN | disclosed |
| US-9617276-B2 | Compounds and methods for treating AIDS and HIV infections | PURDUE RESEARCH FOUNDATION (US) | 2017-04-11 | — | — | US | disclosed |
| US-9617276-B2 | Compounds and methods for treating AIDS and HIV infections | PURDUE RESEARCH FOUNDATION (US) | 2017-04-11 | — | — | US | disclosed |
| US-9497963-B2 | Methods and compositions for control of gypsy moth, Lymantria dispar | SIMON FRASER UNIVERSITY (CA) | 2016-11-22 | — | — | US | disclosed |
| CN-105189510-A | Inhibitors of human immunodeficiency virus replication | BRISTOL MYERS SQUIBB CO | 2015-12-23 | — | — | CN | disclosed |
| US-9125406-B2 | Methods and compositions for control of cabbage looper, trichoplusia ni | SIMON FRASER UNIVERSITY (CA) | 2015-09-08 | — | — | US | disclosed |
| US-20150111962-A1 | COMPOUNDS AND METHODS FOR TREATING AIDS AND HIV INFECTIONS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-04-23 | — | — | US | disclosed |
| US-20150111962-A1 | COMPOUNDS AND METHODS FOR TREATING AIDS AND HIV INFECTIONS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-04-23 | — | — | US | disclosed |
| WO-2009001046-A2 | [11C]METHOXY-RADIOLABELLED 2,3',4,5'-TETRAMETHYLSTILBENE (TMS) AND ITS PREPARATION AND USE | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2008-12-31 | — | — | WO | disclosed |
| EP-0470176-B1 | SUBSTITUTED 3-AMINO CHROMANS | UPJOHN CO (US) | 1993-12-29 | — | — | EP | disclosed |
| EP-0470176-A1 | SUBSTITUTED 3-AMINO CHROMANS. | UPJOHN CO (US) | 1992-02-12 | — | — | EP | disclosed |
| WO-1990012795-A1 | SUBSTITUTED 3-AMINO CHROMANS | THE UPJOHN COMPANY (US) | 1990-11-01 | — | — | WO | disclosed |
| EP-0071358-B1 | BENZOPYRANO(2,3-D)-V-TRIAZOLE INTERMEDIATES | BEECHAM GROUP PLC (GB) | 1986-04-09 | — | — | EP | disclosed |
| EP-0149223-A2 | Novel intermediates | BEECHAM GROUP PLC (GB) | 1985-07-24 | — | — | EP | disclosed |
| EP-0054398-B1 | PHARMACOLOGICALLY ACTIVE BENZOPYRANO-(2,3-D)-V-TRIAZOLES | BEECHAM GROUP PLC (GB) | 1985-03-06 | — | — | EP | disclosed |
| US-4427686-A | ANTIALLERGENS | BEECHAM GROUP LIMITED (GB) | 1984-01-24 | — | — | US | disclosed |
| EP-0071358-A2 | Benzopyrano(2,3-d)-v-triazole intermediates | BEECHAM GROUP PLC (GB) | 1983-02-09 | — | — | EP | disclosed |
| EP-0054398-A1 | Pharmacologically active benzopyrano-(2,3-d)-v-triazoles | BEECHAM GROUP PLC (GB) | 1982-06-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150111962-A1 | COMPOUNDS AND METHODS FOR TREATING AIDS AND HIV INFECTIONS | CTSS, DNPEP, PEPD | MAOB 529/4885LMNA 1784/4885MAPK1 4419/4885 |
| US-20240239774-A1 | SOLUBLE ADENYLYL CYCLASE (SAC) INHIBITORS AND USES THEREOF | UACA, ADCYAP1R1, ADCY1 | MAOB 1249/4885LMNA 3019/4885MAPK1 1159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.