Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL8985996 | 0.79 | NPC1 (0.57) | AKR1C3AKR1C1HTTMEN1KMT2A | |
| Chlorobenzene SCHEMBL28133315 | 0.76 | TSHR (0.50) | AKR1C3AKR1C1HTTMEN1KMT2A | |
| Bromobenzene SCHEMBL28136917 | 0.76 | ALDH1A1 (0.50) | AKR1C3AKR1C1HTTMEN1KMT2A | |
| SCHEMBL11099195 | 0.74 | AKR1C3 (0.66) | AKR1C3AKR1C1GAAMAPTNPC1 | |
| SCHEMBL3126764 | 0.74 | CYP3A4 (0.52) | AKR1C3AKR1C1HTTMEN1KMT2A | |
| SCHEMBL1679860 | 0.72 | ALDH1A1 (0.40) | MAPTALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL3126774 | 0.70 | ALDH1A1 (0.32) | ALDH1A1 | |
| Biphenyl SCHEMBL958818 | 0.70 | HPGD (0.53) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL2809108 | 0.69 | ALDH1A1 (0.38) | MAPTALDH1A1HPGDLMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29742149 | 0.69 | ALDH1A1 (0.38) | MAPTALDH1A1HPGDLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829746-B2 | Process for the preparation of calcipotriol | INSTYTUT FARMACEUTYCZNY (PL) | 2010-11-09 | — | — | US | disclosed |
| US-20100222614-A1 | PROCESS FOR THE PREPARATION OF CALCIPOTRIOL | INSTYTUT FARMACEUTYCZNY (PL) | 2010-09-02 | — | — | US | disclosed |
| EP-2178833-A2 | PROCESS FOR THE PREPARATION OF CALCIPOTRIOL | INSTYTUT FARMACEUTYCZNY (PL) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009008754-A2 | PROCESS FOR THE PREPARATION OF CALCIPOTRIOL | INSTYTUT FARMACEUTYCZNY (PL) | 2009-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222614-A1 | PROCESS FOR THE PREPARATION OF CALCIPOTRIOL | CYP2R1, CYP24A1, DHCR24 | AKR1C3 10/4885AKR1C1 35/4885HTT 4677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.