Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | FASN | P49327 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL958818 | 0.89 | HPGD (0.53) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| Biphenyl SCHEMBL7611759 | 0.85 | RAB9A (0.74) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| Biphenyl SCHEMBL11881576 | 0.85 | RAB9A (0.74) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| Chlorobenzene SCHEMBL28133315 | 0.81 | TSHR (0.50) | NPC1RAB9AMEN1KMT2AAKR1C3 | |
| Biphenyl SCHEMBL3406363 | 0.81 | SMN1; SMN2 (0.62) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| Biphenyl SCHEMBL27470407 | 0.81 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| Bromobenzene SCHEMBL28136917 | 0.81 | ALDH1A1 (0.50) | NPC1RAB9AMEN1KMT2AAKR1C3 | |
| Biphenyl SCHEMBL7614586 | 0.81 | RAB9A (0.63) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL3126764 | 0.79 | CYP3A4 (0.52) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11099195 | 0.79 | AKR1C3 (0.66) | NPC1RAB9AAKR1C3AKR1C1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583000-A | DETECTING PRESENCE OF RETROVIRAL PROTEASES IN SAMPLE BY COMBINING WITH SPECIFIED COMPOUND AND DETECTING PRESENCE OF COMPLEXES FORMED | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-12-10 | — | — | US | disclosed |