Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30983523 | 0.91 | PLA2G2A (0.38) | TLR7FFAR4PLA2G2APTGDR2CNR1 | |
| SCHEMBL30983451 | 0.90 | PLA2G2A (0.38) | TLR7PLA2G2AMAOBPTGDR2SCN1A | |
| SCHEMBL31269035 | 0.90 | CNR1 (0.36) | TLR7FFAR1FFAR4PLA2G2AMAOB | |
| SCHEMBL31269373 | 0.90 | PLA2G2A (0.37) | TLR7PLA2G2AMAOBPTGDR2SCN1A | |
| SCHEMBL31268872 | 0.90 | PLA2G2A (0.37) | TLR7PLA2G2AMAOBPTGDR2SCN1A | |
| SCHEMBL31269020 | 0.90 | FFAR4 (0.38) | TLR7FFAR1FFAR4PTGDR2SCN1A | |
| SCHEMBL31269376 | 0.87 | PPARG (0.34) | TLR7FFAR1PLA2G2AMAOBPTGDR2 | |
| SCHEMBL31268992 | 0.86 | CNR1 (0.35) | TLR7FFAR1FFAR4PLA2G2AMAOB | |
| SCHEMBL31321937 | 0.85 | PLA2G2A (0.40) | PLA2G2A | |
| SCHEMBL31269340 | 0.85 | S1PR1 (0.36) | KDM4EFFAR1FFAR4PLA2G2APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |