Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.35 |
| ▸ | CCR2 | P41597 | 2/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31321937 | 0.93 | PLA2G2A (0.40) | PIK3CDPLA2G2A | |
| SCHEMBL31269288 | 0.91 | PLA2G2A (0.36) | S1PR1S1PR3PIK3CDPLA2G2AFFAR1 | |
| SCHEMBL31269035 | 0.91 | CNR1 (0.36) | PIK3CDPTGDR2S1PR5PLA2G2AFFAR1 | |
| SCHEMBL31269325 | 0.89 | S1PR1 (0.39) | S1PR1PIK3CDPTGDR2S1PR5PDGFRA | |
| SCHEMBL31268849 | 0.88 | PIK3CD (0.37) | S1PR1PIK3CDPTGDR2S1PR5PLA2G2A | |
| SCHEMBL30983523 | 0.87 | PLA2G2A (0.38) | PIK3CDPTGDR2PLA2G2AFFAR4 | |
| SCHEMBL31269149 | 0.87 | CNR1 (0.36) | PIK3CDPLA2G2AFFAR4 | |
| SCHEMBL31268992 | 0.87 | CNR1 (0.35) | PIK3CDPTGDR2S1PR5PLA2G2AFFAR1 | |
| SCHEMBL30983451 | 0.87 | PLA2G2A (0.38) | PIK3CDPTGDR2PLA2G2A | |
| SCHEMBL31268962 | 0.87 | PIK3CD (0.36) | S1PR1PIK3CDS1PR5PLA2G2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |