Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31269133 | 0.94 | PLA2G2A (0.38) | PIK3CDDGAT1CNR1CNR2MAPT | |
| SCHEMBL31269290 | 0.94 | PIK3CD (0.37) | PIK3CDDGAT1CNR1CNR2PDE10A | |
| SCHEMBL31269283 | 0.94 | PIK3CD (0.38) | PIK3CDDGAT1KDM4EALDH1A1CNR1 | |
| SCHEMBL31268852 | 0.92 | PIK3CD (0.36) | PIK3CDDGAT1CNR1MAOBHTR6 | |
| SCHEMBL31268757 | 0.92 | PLA2G2A (0.38) | CXCR2ALDH1A1LMNAADRA1DPLA2G2A | |
| SCHEMBL31269194 | 0.90 | TLR7 (0.36) | PIK3CDDGAT1ADRA1DCNR2 | |
| SCHEMBL31268788 | 0.90 | PIK3CD (0.37) | PIK3CDDGAT1LMNACNR1CNR2 | |
| SCHEMBL30983484 | 0.89 | PIK3CD (0.36) | PIK3CDDGAT1CNR1CNR2 | |
| SCHEMBL31268991 | 0.89 | PIK3CD (0.36) | PIK3CDDGAT1CNR1CNR2PDE10A | |
| SCHEMBL31269255 | 0.89 | PDE10A (0.38) | PIK3CDDGAT1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |