Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | KLK1 | P06870 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31269049 | 0.93 | GPR119 (0.37) | GPR119KLKB1KLK1PIK3CDHCRTR1 | |
| SCHEMBL31269294 | 0.91 | TLR7 (0.35) | TLR7GPR119PIK3CDPDCD1CD274 | |
| SCHEMBL31269133 | 0.90 | PLA2G2A (0.38) | TLR7PIK3CDCNR2DGAT1 | |
| SCHEMBL31268878 | 0.90 | PIK3CD (0.36) | ADRA1DPIK3CDCNR2DGAT1 | |
| SCHEMBL31269290 | 0.90 | PIK3CD (0.37) | PIK3CDROCK2CNR2DGAT1 | |
| SCHEMBL31268852 | 0.89 | PIK3CD (0.36) | PIK3CDHCRTR1HCRTR2ACACBDGAT1 | |
| SCHEMBL31269283 | 0.89 | PIK3CD (0.38) | PIK3CDCNR2DGAT1 | |
| SCHEMBL31269462 | 0.89 | PDE4A (0.36) | GPR119PIK3CDDGAT1 | |
| SCHEMBL31268757 | 0.88 | PLA2G2A (0.38) | CCR2ADRA1D | |
| SCHEMBL31268911 | 0.88 | GPR119 (0.36) | GPR119PIK3CDHCRTR1HCRTR2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |