Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 14/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | INSR | P06213 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31269245 | 0.97 | PIK3CD (0.35) | PIK3CDTLR7AXLKCNH2INSR | |
| SCHEMBL31269192 | 0.96 | PIK3CD (0.37) | PIK3CDTLR7 | |
| SCHEMBL31269162 | 0.91 | PIK3CD (0.35) | PIK3CDKCNH2IGF1R | |
| SCHEMBL31269315 | 0.91 | PIK3CD (0.36) | PIK3CD | |
| SCHEMBL31268923 | 0.89 | PIK3CD (0.34) | PIK3CD | |
| SCHEMBL31269013 | 0.89 | PIK3CD (0.39) | PIK3CD | |
| SCHEMBL31269089 | 0.88 | PIK3CD (0.34) | PIK3CD | |
| SCHEMBL31269171 | 0.85 | DRD2 (0.37) | PIK3CDTLR7 | |
| SCHEMBL30983492 | 0.85 | PIK3CD (0.38) | PIK3CDCNR1KCNH2 | |
| SCHEMBL30983598 | 0.85 | PIK3CD (0.38) | PIK3CDCNR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |