Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 5/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 3/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.31 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.31 |
| ▸ | USP7 | Q93009 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31269162 | 0.97 | PIK3CD (0.35) | PIK3CDDYRK1AUSP7 | |
| SCHEMBL31269013 | 0.93 | PIK3CD (0.39) | PIK3CD | |
| SCHEMBL31269245 | 0.89 | PIK3CD (0.35) | PIK3CD | |
| SCHEMBL31268969 | 0.89 | PIK3CD (0.37) | PIK3CD | |
| SCHEMBL31269089 | 0.88 | PIK3CD (0.34) | PIK3CD | |
| SCHEMBL31268847 | 0.87 | KCNH2 (0.36) | PIK3CDDYRK1AKDM1AUSP7 | |
| SCHEMBL31269192 | 0.87 | PIK3CD (0.37) | PIK3CD | |
| SCHEMBL31321958 | 0.86 | PIK3CD (0.40) | PIK3CDDYRK1A | |
| SCHEMBL31269315 | 0.85 | PIK3CD (0.36) | PIK3CD | |
| SCHEMBL31269436 | 0.85 | CHRNA3 (0.36) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |