Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK1 | Q13153 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | USP1 | O94782 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | ROS1 | P08922 | 1/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31269236 | 0.95 | PIK3CD (0.34) | PAK1PIK3CDKCNH2SCN5ASCN9A | |
| SCHEMBL31268880 | 0.91 | PIK3CD (0.32) | PAK1PIK3CDKCNH2SCN5ASCN9A | |
| SCHEMBL31269036 | 0.89 | SLC6A2 (0.34) | PIK3CDKCNH2SCN5ASCN9ACNR1 | |
| SCHEMBL31268826 | 0.89 | PTGS2 (0.34) | PIK3CDKCNH2SCN5ASCN9A | |
| SCHEMBL31269289 | 0.89 | PIK3CD (0.34) | PIK3CDKCNH2SCN5ASCN9ACNR1 | |
| SCHEMBL31269053 | 0.87 | DGAT1 (0.35) | PIK3CDKCNH2SCN5ASCN9ACNR1 | |
| SCHEMBL31269375 | 0.87 | PIK3CD (0.37) | PIK3CDKCNH2SCN5ASCN9ACNR1 | |
| SCHEMBL31269374 | 0.86 | PDK2 (0.36) | PIK3CDKCNH2SCN5ASCN9A | |
| SCHEMBL31269215 | 0.85 | KCNH2 (0.34) | PIK3CDKCNH2SCN5ASCN9ACNR1 | |
| SCHEMBL31269475 | 0.84 | PIK3CD (0.37) | PIK3CDKCNH2SCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |