Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31268830 | 0.94 | DPP4 (0.35) | DPP4PIK3CDGPR119 | |
| SCHEMBL31269337 | 0.91 | CNR1 (0.39) | DPP4PIK3CDGPR119 | |
| SCHEMBL31268788 | 0.89 | PIK3CD (0.37) | PIK3CD | |
| SCHEMBL31268911 | 0.88 | GPR119 (0.36) | PIK3CDGPR119 | |
| SCHEMBL31269049 | 0.87 | GPR119 (0.37) | PIK3CDGPR119 | |
| SCHEMBL31268852 | 0.86 | PIK3CD (0.36) | DPP4PIK3CD | |
| SCHEMBL31269283 | 0.85 | PIK3CD (0.38) | PIK3CDKCNH2 | |
| SCHEMBL31268747 | 0.84 | CNR1 (0.36) | PIK3CD | |
| SCHEMBL31269194 | 0.84 | TLR7 (0.36) | PIK3CDGPR119 | |
| SCHEMBL31269290 | 0.84 | PIK3CD (0.37) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |