Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 8/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31268895 | 0.96 | PDCD1 (0.36) | CD274PDCD1PTGER1FFAR4PIK3CD | |
| SCHEMBL31269428 | 0.91 | PDCD1 (0.34) | CD274PDCD1PTGER1PIK3CDADORA3 | |
| SCHEMBL30983441 | 0.90 | PDCD1 (0.36) | CD274PDCD1PTGER1PIK3CDPTGDR2 | |
| SCHEMBL30983843 | 0.86 | PDCD1 (0.36) | CD274PDCD1PIK3CDADORA3TSHR | |
| SCHEMBL31269249 | 0.86 | PDCD1 (0.34) | CD274PDCD1PTGER1PIK3CDADORA3 | |
| SCHEMBL31269222 | 0.85 | CD274 (0.35) | CD274PDCD1PTGER1PIK3CDADORA3 | |
| SCHEMBL30983814 | 0.85 | PDCD1 (0.34) | CD274PDCD1PIK3CDADORA3USP2 | |
| SCHEMBL30983813 | 0.85 | PDCD1 (0.34) | CD274PDCD1PIK3CDADORA3USP2 | |
| SCHEMBL30983431 | 0.84 | PDCD1 (0.34) | CD274PDCD1PTGER1PIK3CDCTSA | |
| SCHEMBL30984001 | 0.84 | ADORA3 (0.35) | CD274PDCD1PIK3CDADORA3USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |