Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 3/20 | 0.32 |
| ▸ | RXRB | P28702 | 3/20 | 0.32 |
| ▸ | RXRG | P48443 | 2/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31268849 | 0.95 | PIK3CD (0.37) | CNR1CNR2PIK3CDALOX5APPLA2G2A | |
| SCHEMBL31321937 | 0.92 | PLA2G2A (0.40) | PIK3CDPLA2G2ARXRARXRBRXRG | |
| SCHEMBL31268962 | 0.92 | PIK3CD (0.36) | CNR1CNR2PIK3CDPLA2G2ARXRA | |
| SCHEMBL31269288 | 0.87 | PLA2G2A (0.36) | PIK3CDALOX5APPLA2G2ATHRATHRB | |
| SCHEMBL31269035 | 0.87 | CNR1 (0.36) | CNR1PIK3CDPLA2G2AFFAR4PPARG | |
| SCHEMBL31269340 | 0.87 | S1PR1 (0.36) | PIK3CDPLA2G2AFFAR4 | |
| SCHEMBL31269325 | 0.85 | S1PR1 (0.39) | PIK3CDALOX5APPLA2G2ATHRATHRB | |
| SCHEMBL30983954 | 0.84 | PLA2G2A (0.39) | CNR1CNR2PIK3CDALOX5APPLA2G2A | |
| SCHEMBL30983583 | 0.84 | PIK3CD (0.34) | CNR1CNR2PIK3CDPLA2G2A | |
| SCHEMBL30983523 | 0.84 | PLA2G2A (0.38) | CNR1PIK3CDPLA2G2AFFAR4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |